Ever since the FDA slashed the limits on acetaminophen from up to 750 milligrams (mg) to up to 325 mg, there has been an 11% to 16% annual drop in the number of hospitalizations and acute liver failure cases involving combo drugs.
from WebMD Health https://www.webmd.com/pain-management/news/20230309/fda-mandated-tweak-to-common-rx-painkillers-may-have-saved-lives?src=RSS_PUBLIC
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