The British researchers found that in heart disease patients who are obese, body fat surrounding the arteries tends to secrete high amounts of a protein called WNT5A. The protein, in turn, appears to have "toxic" effects within the blood vessels.
from WebMD Health https://www.webmd.com/heart-disease/news/20190919/scientists-discover-new-way-fat-harms-your-arteries?src=RSS_PUBLIC
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